Endoscopic and histological findings in the gastric mucosa of cholecystectomized patients with biliary reflux
DOI:
https://doi.org/10.5281/zenodo.14961672Keywords:
bile reflux, cholecystectomy, histology, gastric mucosaAbstract
Introduction: duodenogastric biliary reflux is one of the main factors of gastric mucosal injury, occurring in 80% to 90% of patients undergoing gallbladder surgery.
Objective: To characterize cholecystectomized patients with biliary reflux and gastric mucosal lesions.
Method: a cross-sectional descriptive study was conducted in 146 cholecystectomized patients who underwent upper gastrointestinal endoscopy in the Gastroenterology Department of the Hospital General Provincial “Carlos Manuel de Céspedes”, Granma province, Cuba, from October 2019 to May 2022. Data were collected from medical records and a survey form; sociodemographic, clinical, endoscopic, and histological variables were analyzed. Quantitative variables were compared using Student's t-test if they had a normal distribution; The qualitative variables were compared as they were analyzed in contingency tables, with the Z test for comparing proportions and the Chi-square test to establish dependence between them.
Results: the mean age was 55.7 years, 53.4% were women, and the mean time since cholecystectomy was 7 years. Sessile polypoid lesions were the most frequently diagnosed endoscopic diagnosis (26.03%), with more than one lesion detected in 17.8%. A total of 41.1% presented pathological elements of chronic superficial gastritis. Men had a higher proportion of cancer compared to women (13.2% vs. 3.8%).
Conclusions: Chronic superficial gastritis and chronic multifocal gastritis were the main histological findings.
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Copyright (c) 2025 Natalies Noemí Ocaña Chávez, Gloria Mabel Martí Garcés, Jorge Omar Cabrera Lavernia, Yoel Mario Ricardo Serrano, Reyner Clavel Rosales
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