Theoretical bases on coronavirus-2 infection in the renal system
Keywords:
COVID-19, acute renal failure, acute renal injuryAbstract
Introduction: the infection for coronavirus-2, which causes the infectious disease known as COVID-19, often affects the renal function in many of the patients.
Objective: to offer a theoretical referent, to contribute on the preparation of medicine students and general doctors about the influence of the infection for coronavirus-2 on the renal system.
Method: in the Hospital Dr. Agostinho Neto, between March and June of 2020, a narrative review about this topic was made through a search in the bibliographical databases Pubmed/Medline, Science Direct and SciELO.
Results: the information was structured as: general aspects of the COVID-19, physiopathology, symptoms, therapeutic bases, prognosis, and social impact of the nephropathy caused by COVID-19. Unsettled aspects regarding the renal failure caused by this pandemic were also identified.
Conclusions: the patient's prognostic with COVID-19 is worsened by the presence of acute renal failure; nevertheless, in the physiopathology, the clinical manifestations and patient prognosis on this complication are not completely known. Its appearance is more common in patients with an antecedent of chronic kidney failure, diabetes mellitus and systemic arterial hypertension which legitimates the necessity of professional preparation to be capable of a precise evaluation of the renal system for prevention and control of this complication.
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References
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18.Qian JY, Wang BB, Cheng L. Acute kidney injury in the 2019 novel coronavirus disease. Kidney Dis (Basel) [en línea] 2020 Jun [citado 14 Jul 2020]; 323: 1-6. Disponible en: 10.1159/000509086
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22.Pan XW, Xu D, Zhang H, Zhou W, Wang LH, Cui XG. Identification of a potential mechanism of acute kidney injury during the COVID-19 outbreak: a study based on single-cell transcriptome analysis. Inten Care Med [en línea] 2020 [citado 14 Jul 2020]; 46(6):1114-1116. Disponible en: https://doi.org/10.1007/s00134-020-06026-1
23.Li Z, Wu M, Yao J, Guo J, Liao X, Song S, et al. Caution on kidney dysfunction of 2019-nCoV patients. Med Rxiv preprint [en línea]. 2020 [citado 14 Jul 2020]; [aprox. 25 p.]. Disponible en: https://doi.org/10.1101/2020.02.08.20021212
24.Durvasula R, Wellington T, McNamara E, Watnick S. COVID-19 and kidney failure in the acute. Am J Kidney Dis [en línea]. 2020 [citado 14 Jul 2020]; 76(1):4-6. Disponible en: https://doi.org/10.1053/j.ajkd.2020.04.001
25.Ronco C, Reis T, Husain-Syed F. Management of acute kidney injury in patients with COVID-19. Lancet Resp Med [en línea]. 2020 [citado 14 Jul 2020]; 8:738-42. Disponible en: https://doi.org/10.1016/S2213-2600(20)30229-0
26.Sun DQ, Wang TY, Zheng KI, Targher G, Byrne CD, Chen YP, Zheng MH. Subclinical acute kidney injury in COVID-19 patients: a retrospective cohort study. Nephron [en línea]. 2020 [citado 14 Jul 2020]; 44:347-350. Disponible en: https://doi.org/10.1159/000508502
27.Martinez RMA, Vega VO, Bobadilla NA. Is the kidney a target of SARS-CoV-2? Am J Phys Renal Physiol [en línea]. 2020 [citado 14 Jul 2020]; 318:F1454–F1462. Disponible en: https://doi.org/10.1152/ajprenal.00160.2020
28.Cheng Y, Luo R, Wang K, Wang K, Zhang M, Wang z, et al. Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney Inter [en línea]. 2020 [citado 14 Jul 2020]; 97:829-838. Disponible en: https://doi.org/10.1016/j.kint.2020.03.005
29.Cheng Y, Luo R, Wang K, Zhang M, Wang Z, Dong L, et al. Kidney impairment is associated with in-hospital death of Covid-19 patients. Med Rxiv preprint [en línea]. 2020 [citado 14 Jul 2020]; [aprox. 21 p.]. Disponible en: https://doi.org/10.1101/2020.02.18.20023242
30.Abbate M, Rottoli D, Gianatti A. COVID-19 Attacks the Kidney: Ultrastructural evidence for the presence of virus in the glomerular epithelium. Nephron [en línea]. 2020 [citado 14 Jul 2020]; 144:341-342. Disponible en: https://doi.org/10.1159/000508430
2. World Health Organization. WHO Director-General’s opening remarks at the media briefing on COVID-19 [en línea]. 2020 [citado 14 Jul 2020]; [aprox. 5 p.]. Disponible en: https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19-11-march-2020
3. World Health Organization. Coronavirus disease 2019 (COVID-19). Situation Report, 101 [en línea]. 2020 [citado 14 Jul 2020]; [aprox. 5 pp.]. Disponible en: https://apps.who.int/iris/hanjdle/10665/332054
4. Cuba. Ministerio de Salud Pública. Parte de cierre del día 22 de marzo de 2020 a las 12 de la noche [en línea]. 2020 [citado 14 Jul 2020]; [aprox. 5 p.]. Disponible en: https://salud.msp.gob.cu/?p=5681
5. Aleebrahim DE, Reyhanian A, Saberianpour S, Hasanpour DA. Acute kidney injury in COVID-19; a review on current. J Nephropathol [en línea]. 2020 [citado 14 Jul 2020]; 9(4):e31. Disponible en: 10.34172/jnp.2020.31
6. Capuano I, Buonanno P, Riccio E, Pisani A. Acute Kidney Injury in COVID-19 Pandemic. Nephron [en línea]. 2020 [citado 14 Jul 2020]; 144:345-346. Disponible en: https://doi.org/10.1159/000508381
7. Gabarre P, Dumas G, Dupont T, Darmon M, Azoulay E, Zafrani L. Acute kidney injury in critically ill patients with COVID‑19. Intens Care Med [en línea]. 46(7):1-10. [citado 14 Jul 2020]. Disponible en: https://doi.org/10.1007/s00134-020-06153-9
8. Grossa O. COVID-19-associated nephritis: early warning for disease severity and complications?. Lancet [en línea] 2020 [citado 14 Jul 2020]; 395(10236):e87-e88. Disponible en: https://doi.org/10.1016/S0140-6736(20)31041-2
9. Hirsch JS, Jia HN, Ross DW, Sharma P, Shah HH, Barnett RL, et al. Acute kidney injury in patients hospitalized with COVID-19. Kidney Intern [en línea] 2020 [citado 14 Jul 2020]; 98:209-218. Disponible en: https://doi.org/10.1016/j.kint.2020.05.006
10.Larsen CP, Bourne TD, Wilson JD, Saqqa O, Sharshir MA. Collapsing glomerulopathy in a patient with coronavirus disease 2019 (COVID-19). Kidney Int Rep [en línea]. 2020 Jun [citado 14 Jul 2020]; 5(6):935-939. Disponible en: 10.1016/j.ekir.2020.04.002
11.Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. The proximal origin of SARS-CoV-2. Nat Med [en línea]. 2020 [citado 14 Jul 2020]. 26(4): 450-455. Disponible en: 10.1038/s41591-020-0820-9
12.Wu P, Hao X, Lau EHY, Wong JY, Leung KSM, Wu JT, et al. Real time tentative assesment of the epidemiological characteristics of novel coronavirus infections in Wuhan, China, as at 22 January, 2020. Euro Surveill [en línea]. 2020 [citado 14 Jul 2020]; 25(3):pii2000044. Disponible en: 10.2807/1560-7917.ES.2020.25.3.2000044
13.Rothan HA, Siddappa NB. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoim [en línea]. 2020 May [citado 14 Jul 2020]; 109:[aprox. 8 p.]. Disponible en: 10.1016/j.jaut.2020.102433
14.García SA. Revisión narrativa sobre la respuesta inmunitaria frente a coronavirus: descripción general, aplicabilidad para SARS-COV-2 e implicaciones terapéuticas. An Pediatr (Barc) [en línea]. 2020 Jul [citado 14 Jul 2020]; 93(1):60.e1–60.e7. Disponible en: 10.1016/j.anpedi.2020.04.016
15.Moitinho MS, Belasco AGS, Barbosa DA, Fonseca CD. Acute Kidney Injury by SARS-CoV-2 virus in patients with COVID-19: an integrative review. Rev Bras Enferm [en línea]. 2020 [citado 14 Jul 2020]; 73(Suppl 2):e20200354. Disponible en: 10.1590/0034-7167-2020-0354
16.Naicker S, Yang CW, Hwang SJ, Liu BCh, Chen JH, Jha V. The novel coronavirus 2019 epidemic and kidneys. Kidney Intern [en línea] 2020 [citado 14 Jul 2020]; 97(5):824-828. Disponible en: 10.1016/j.kint.2020.03.001
17.Pei G, Zhang Z, Peng J, et al. Renal involvement and early prognosis in patients with COVID-19 pneumonia. J Am Soc Nephrol [en línea]. 2020 [citado 14 Jul 2020]; 31(6): 1157-1165. Disponible en: https://jasn.asnjournals.org/content/31/6/1157
18.Qian JY, Wang BB, Cheng L. Acute kidney injury in the 2019 novel coronavirus disease. Kidney Dis (Basel) [en línea] 2020 Jun [citado 14 Jul 2020]; 323: 1-6. Disponible en: 10.1159/000509086
19.Zhang Y, Hong Zhang. Genetic roadmap for kidney involvement of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infection. CJASN [en línea]. 2020 [citado 14 Jul 2020]; 15(7):1044-1046. Disponible en: https://doi.org/10.2215/CJN.04370420
20.Su H, Yang M, Wan C, et al. Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China. Kidney Int [en línea]. 2020 Jul [citado 14 Jul 2020]; 98(1):219-227. Disponible en: 10.1016/j.kint.2020.04.003
21.Ronco C, Reis T. Kidney involvement in COVID-19 and rationale for extracorporeal therapies. Nat Rev Nephrol [en línea]. 2020 Jul [citado 14 Jul 2020]; 16(6):308-310. Disponible en: https://doi.org/10.1038/s41581-020-0284-7
22.Pan XW, Xu D, Zhang H, Zhou W, Wang LH, Cui XG. Identification of a potential mechanism of acute kidney injury during the COVID-19 outbreak: a study based on single-cell transcriptome analysis. Inten Care Med [en línea] 2020 [citado 14 Jul 2020]; 46(6):1114-1116. Disponible en: https://doi.org/10.1007/s00134-020-06026-1
23.Li Z, Wu M, Yao J, Guo J, Liao X, Song S, et al. Caution on kidney dysfunction of 2019-nCoV patients. Med Rxiv preprint [en línea]. 2020 [citado 14 Jul 2020]; [aprox. 25 p.]. Disponible en: https://doi.org/10.1101/2020.02.08.20021212
24.Durvasula R, Wellington T, McNamara E, Watnick S. COVID-19 and kidney failure in the acute. Am J Kidney Dis [en línea]. 2020 [citado 14 Jul 2020]; 76(1):4-6. Disponible en: https://doi.org/10.1053/j.ajkd.2020.04.001
25.Ronco C, Reis T, Husain-Syed F. Management of acute kidney injury in patients with COVID-19. Lancet Resp Med [en línea]. 2020 [citado 14 Jul 2020]; 8:738-42. Disponible en: https://doi.org/10.1016/S2213-2600(20)30229-0
26.Sun DQ, Wang TY, Zheng KI, Targher G, Byrne CD, Chen YP, Zheng MH. Subclinical acute kidney injury in COVID-19 patients: a retrospective cohort study. Nephron [en línea]. 2020 [citado 14 Jul 2020]; 44:347-350. Disponible en: https://doi.org/10.1159/000508502
27.Martinez RMA, Vega VO, Bobadilla NA. Is the kidney a target of SARS-CoV-2? Am J Phys Renal Physiol [en línea]. 2020 [citado 14 Jul 2020]; 318:F1454–F1462. Disponible en: https://doi.org/10.1152/ajprenal.00160.2020
28.Cheng Y, Luo R, Wang K, Wang K, Zhang M, Wang z, et al. Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney Inter [en línea]. 2020 [citado 14 Jul 2020]; 97:829-838. Disponible en: https://doi.org/10.1016/j.kint.2020.03.005
29.Cheng Y, Luo R, Wang K, Zhang M, Wang Z, Dong L, et al. Kidney impairment is associated with in-hospital death of Covid-19 patients. Med Rxiv preprint [en línea]. 2020 [citado 14 Jul 2020]; [aprox. 21 p.]. Disponible en: https://doi.org/10.1101/2020.02.18.20023242
30.Abbate M, Rottoli D, Gianatti A. COVID-19 Attacks the Kidney: Ultrastructural evidence for the presence of virus in the glomerular epithelium. Nephron [en línea]. 2020 [citado 14 Jul 2020]; 144:341-342. Disponible en: https://doi.org/10.1159/000508430
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Published
2020-09-14
How to Cite
1.
Maceo-Sobrado E, Elias-Armas KS, Poll-Fernández A, Paumier-Galano E. Theoretical bases on coronavirus-2 infection in the renal system. Rev Inf Cient [Internet]. 2020 Sep. 14 [cited 2025 Apr. 16];99(3):274-83. Available from: https://revinfcientifica.sld.cu/index.php/ric/article/view/2913
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Review Articles
