Invasive mole. Case presentation
Keywords:
invasive mole, gestational trophoblastic diseaseAbstract
A case of trophoblastic disease, of the invasive mole type was presented. The diagnosis was first suspected with the ultrasound of the first genetic marker. Two therapeutic curettages were performed, the second of which suggested the diagnosis of invasive mole. Surgical treatment (total hysterectomy) was performed with prior administration of chemotherapy with systemic methotrexate. The biopsy confirmed the diagnosis of invasive mole. Invasive mole is one of the forms of presentation of gestational trophoblastic disease. It is a rare condition in which the proliferation of trophoblast and syncytiotrophoblast cells penetrate or even perforate the uterine wall, produce local damage and can invade the parametrial tissue and blood vessels, traveling within these. True metastatic seeding in other organs has not been reported. The clinical evolution was carried out in an outpatient clinic. After two years the evolution is satisfactory, the treatment effective and well tolerated by the patient.
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2. Seyedeh Reyhaneh YS, Saffarieh E. A review on management of gestational trophoblastic neoplasia. J Fam Med Prim Care [Internet]. 2020 [citado 13 May 2021]; 9(3):1287-95. Disponible en: https://www.jfmpc.com/article.asp?issn=2249-4863;year=2020;volume=9;issue=3;spage=1287;epage=1295;aulast=Sharami
3. Huanca-Llamo J, Aranzabal-Alegria G, Chanduvil W. Factores asociados a enfermedad trofoblástica gestacional en un Hospital de Referencia Peruano. Rev Fac Med Hum [Internet]. 2020 Ene [citado 15 May 2021]; 20(1):64-69. Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S2308-05312020000100064&lng=es
4. Gary Cunningham F, Kenneth JL, Steven LB, Jodi SD, Hoffman BL, et al. Enfermedad trofoblástica gestacional. En: Williams Obstetrics. 25ed. New York: McGraw-Hill Education; 2019. p:257-65.
5. Espinoza Artavia A, Fernández Vaglio R, Solar Del Valle T. Actualización en patología trofoblástica gestacional: mola hidatiforme y neoplasias. Rev Méd Sinergia [Internet]. 2019 [citado 14 May 2021]; 4(5):44-59. Disponible en: https://www.medigraphic.com/pdfs/sinergia/rms-2019/rms195e.pdf
6. Carrillo Bermúdez L, Alonso Llanes Y, Gutiérrez Herrera M, Couret Cabrera MP, Festary Casanova A, Pino Rivera G. Mola hidatiforme parcial del segundo trimestre. Rev Cubana Obst Gin [Internet]. 2018 Jun [citado 15 May 2021]; 44(2):1-11. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-600X2018000200014&lng=es
7. Illegas Mejía CR, Chacón Cardona JA, Villegas Jaramillo M. Enfermedad trofoblástica gestacional en un centro oncológico de Caldas-Colombia durante el periodo 2001 2014. Medicas UIS [Internet]. 2017 Dec [citado 15 May 2021]; 30(3):39-49. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0121-03192017000300039&lng=en
8. Durón González R, Bolaños Morera P. Enfermedad trofoblástica gestacional. Med Legal Costa Rica [Internet]. 2018 [citado 15 May 2021]; 35(1). Disponible en: https://www.scielo.sa.cr/pdf/mlcr/v35n1/1409-0015-mlcr-35-01-30.pdf
9. Yánez Monteros S. Maruri G, Avila D. Diagnóstico ecográfico de embarazo molar, simultaneo con feto vivo. Rev Latin Perinat [Internet]. 2019, [citado 14 May 2021]; 22(4):260. Disponible en: http://www.revperinatologia.com/images/9_Rev_lat_perinat_Vol_22_4_2019.pdf
10.Martínez Camilo RV. Mola invasiva. Rev Cubana Obst Gin [Internet]. 2016 Sep [citado 15 May 2021]; 42(3):366-371. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-600X2016000300012&lng=es