Invasive mole. Case presentation

Authors

Keywords:

invasive mole, gestational trophoblastic disease

Abstract

A case of trophoblastic disease, of the invasive mole type was presented. The diagnosis was first suspected with the ultrasound of the first genetic marker.  Two therapeutic curettages were performed, the second of which suggested the diagnosis of invasive mole. Surgical treatment (total hysterectomy) was performed with prior administration of chemotherapy with systemic methotrexate. The biopsy confirmed the diagnosis of invasive mole. Invasive mole is one of the forms of presentation of gestational trophoblastic disease. It is a rare condition in which the proliferation of trophoblast and syncytiotrophoblast cells penetrate or even perforate the uterine wall, produce local damage and can invade the parametrial tissue and blood vessels, traveling within these. True metastatic seeding in other organs has not been reported. The clinical evolution was carried out in an outpatient clinic. After two years the evolution is satisfactory, the treatment effective and well tolerated by the patient.

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Author Biographies

Orlando Sanamé-Columbié, Hospital General Docente "Octavio de la Concepción y de la Pedraja", Baracoa

Especialista de I Grado en Anatomía Patológica. Asistente.

Osmany Jiménez-Lobaina, Hospital General Docente "Octavio de la Concepción y de la Pedraja", Baracoa

Especialista de I Grado en Anatomía Patológica. Instructor.

Williams Jiménez-Reyes, Hospital General Docente "Octavio de la Concepción y de la Pedraja", Baracoa

Especialista de II Grado en Ginecología y Obstetricia y en Perinatología. Asistente. Investigador Auxiliar.

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Published

2021-09-29

How to Cite

1.
Sanamé-Columbié O, Jiménez-Lobaina O, Jiménez-Reyes W. Invasive mole. Case presentation. Rev Inf Cient [Internet]. 2021 Sep. 29 [cited 2025 Jun. 21];100(5):e3515. Available from: https://revinfcientifica.sld.cu/index.php/ric/article/view/3515