Effectiveness of Frey's surgery in patients with chronic pancreatitis of the General Teaching Hospital "Dr. Agostinho Neto ", Guantanamo
Keywords:
chronic pancreatitis, resective and derivative procedures, Frey´s surgeryAbstract
Introduction: chronic pancreatitis is the inflammation of the multiple-cause pancreatic gland, which produces pain and damage to the parenchyma, progressive and irreversible, with fibrosis and stenosis of the ducts. Among its treatments is the local resection of the head of the pancreas (excavation) with laterolateral pancreaticojejunostomy, known as Frey's surgery. Objective: to demonstrate the effectiveness of Frey's surgery for patients with pain due to chronic pancreatitis. Method: a descriptive and prospective study was carried out in 8 patients suffering from chronic pancreatitis operated in the General Surgery Department of the General Teaching Hospital "Dr. Agostinho Neto ", Guantanamo, to whom Frey's surgery was applied. The variables were analyzed: average age, sex, personal pathological history, average time of surgery, average blood transfusion, morbidity, mortality and average follow-up. Results: the average age was 51 years, the predominant sex was male and alcoholism was the first cause of chronic pancreatitis. The main conduit of the pancreas had an average diameter of 13.8 mm and the head of the pancreas had an average measurement of 49 mm; the surgical time averaged 282 min and the average blood transfusion was 506.25 ml. Postoperative morbidity was 25.0% and there was no mortality. The follow-up of the patients obtained an average of 42.25 months and 87.56% reported absence of pain after the intervention. During follow-up there was no new onset diabetes or steatorrhea. Conclusions: frey's surgery is safe, effective and with good results to treat the pain of chronic pancreatitis, especially those with an inflammatory mass in the head of the pancreas, so the authors recommend its use.Downloads
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References
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17.Roch A, Teyssedou J, Mutter D, Marescaux J, Pessaux P. Chronic pancreatitis: A surgical disease? Role of the Frey procedure. World J Gastrointest Surg [en línea]. 2014 [citado 17 Oct 2018]; 6(7):129-135. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110530/
18.Frey CF, Amikura K. Local resection of the head of the pancreas combined with longitudinal pancreaticojejunostomy in the management of patients with chronic pancreatitis. Ann Surg [en línea]. 1994 [citado 17 Oct 2018]; 220(4):492-507. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1234422/
2. Gestic MA, Callejas-Neto F, Chaim A, Utrini MP, Cazzo E, Pareja JC. Surgical treatment of chronic pancreatitis using Frey's procedure: a Brazilian 16-year single-centre experience. HPB (Oxford) [en línea]. 2011 [citado 17 Oct 2018]; 13(4): 263-271. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/21418132
3. Casaba SM, Venugopal HG, Nagesh NS, Karlwad S, Sathish O, Vinay BN, Prasanna B. Frey’s procedure- to analyse the outcome of this procedure in chronic pancreatitis. J. Evid. Based Med Healthc [en línea]. 2017 [citado 17 Oct 2018]; 4(29):1695-1699. Disponible en: https://www.ingentaconnect.com/content/doaj/23492562/2017/00000004/00000029/art00005
4. Piriz Momblant A. Pancreatitis crónica. Resultados quirúrgicos. Rev Inf Cient [en línea]. 2004 [citado 19 Jul 2018]; 42(2):1-9. Disponible en: http://www.revinfcientifica.sld.cu/index.php/ric/article/view/1575/2981
5. Ni Q, Yun L, Roy M, Shang D. Advances in surgical treatment of chronic pancreatitis. World J Sur Oncol [en línea]. 2015 [citado 17 Oct 2018]; 13: 34-39. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326204/
6. Levy P, Dominguez Muñoz E, Imrie C, Matthias Löhr M, Maisonneuve P. Epidemiology of chronic pancreatitis: burden of the disease and consequences. United Eur Gastroenterol J [en línea]. 2014 [citado 17 Oct 2018]; 2: 345–354. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/25360312
7. Machicado JD, Rebours V, Yadav D. Epidemiology of Chronic Pancreatitis. Pancreapedia. Exocrine Pancreas Knowledge Base [en línea]. 2016 [citado 17 Oct 2018]. DOI: 10.3998/panc.2016.13
8. Majumder S, Chari ST. Chronic pancreatitis. Lancet [en línea]. 2016 [citado 17 Oct 2018]; 387: 1957–1966. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/26948434
9. Piriz Momblant A. Páncreas. Técnicas quirúrgicas. La Habana: ECIMED; 2010.
10.Suzumura K, Hatano E, Okada T, Asano Y, UyamaN, Nakamura Y, Hai S, Fujimoto J. Short and long term outcomes of the Frey procedure for chronic pancreatitis: a single center experience and summary of outcomes in Japan. Surg Today [en línea]. 2018 [citado 17 Oct 2018]; 48:58–65. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/28597350
11.Ueda J, Miyasaka Y, Ohtsuka, Takahata, Tanaka M. Short- and long-term results of the Frey procedure for chronic pancreatitis. J Hepatobiliary Pancreat Sci [en línea]. 2015 [citado 17 Oct 2018]; 22(3):211–216. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/25339262
12.Tan C L, Zhang H, Yang M, Li S J, Liu X B, Li K Z. Role of original and modified Frey's procedures in chronic pancreatitis. World J Gastroenterol [en línea]. 2016 [citado 17 Oct 2018]; 22:10415-10423. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/28058022
13.Zhao X, Cui N, Wang X, Cui Y. Surgical strategies in the treatment of chronic pancreatitis. An updated systematic review and meta-analysis of randomized controlled trials. Medicine [en línea]. 2017 [citado 17 Oct 2018]; 96(9): 1-13. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/28248878
14.Aimoto T, Uchida E, Matsushita E, Kawano Y, Mizutani S, Kobayashi T. Long-term outcomes after Frey`s procedure for chronic pancreatitis with inflammatory mass of the pancreatic head with special reference to locoregional complications. J Nippon Med Sch [en línea]. 2013 [citado 17 Oct 2018]; 80(2):148-154. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/23657068
15.Tanaka M, Matsumoto I, Shinzeki M, Asari S, Goto T, Yamashita H, Ishida J, Ajiki T, Fukumoto T, Ku Y. Short- and Long-term Results of Modified Frey’s Procedure in Patients with Chronic Pancreatitis: A Retrospective Japanese Single-Center Study. Kobe J Med Sci [en línea]. 2014 [citado 17 Oct 2018]; 60(2):E30-E36. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/25339257
16.Pessaux P, Kianmanesh R, Regimbeau J M, Sastre B, Delcenserie R, Sielezneff I, Arnaud J P, Sauvanet A. Frey Procedure in the Treatment of Chronic Pancreatitis Short-term Results. Pancreas [en línea]. 2006 [citado 17 Oct 2018]; 33(4):354-358. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/17079939
17.Roch A, Teyssedou J, Mutter D, Marescaux J, Pessaux P. Chronic pancreatitis: A surgical disease? Role of the Frey procedure. World J Gastrointest Surg [en línea]. 2014 [citado 17 Oct 2018]; 6(7):129-135. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110530/
18.Frey CF, Amikura K. Local resection of the head of the pancreas combined with longitudinal pancreaticojejunostomy in the management of patients with chronic pancreatitis. Ann Surg [en línea]. 1994 [citado 17 Oct 2018]; 220(4):492-507. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1234422/
Published
2018-10-23
How to Cite
1.
Piriz Momblant A, Herrera Puentes A, Knight Fernández H. Effectiveness of Frey’s surgery in patients with chronic pancreatitis of the General Teaching Hospital "Dr. Agostinho Neto ", Guantanamo. Rev Inf Cient [Internet]. 2018 Oct. 23 [cited 2025 Apr. 19];97(4):744-5. Available from: https://revinfcientifica.sld.cu/index.php/ric/article/view/2079
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