Obstetric antiphospholipid syndrome and its prevalence in Ecuador
Keywords:
antiphospholipid syndrome, gestation, spontaneous abortion, obstetricsAbstract
Introduction: obstetric antiphospholipid syndrome during pregnancy is a disorder specialized in recurrent venous and arterial thromboembolic events or morbidities during pregnancy. Objective: to characterize the obstetric antiphospholipid syndrome and its prevalence in Ecuador, in the period 2020-2022. Method: qualitative and quantitative study is carried out. The research population included all pregnant women in Ecuador in the period 2020-2022 and who had a diagnosis of obstetric antiphospholipid syndrome or diseases related to it. Several numerical variables were addressed, such as age; the data were obtained from the Institute of Statistics and Census (INEC). Scientific articles published in SciELO, medical journals, medical books and degree works were consulted. Results: the investigation showed that the province of Pichincha, with 26%, has the highest number of cases of obstetric antiphospholipid syndrome, where 605 cases are registered nationwide. Within the study population, inclusion criteria were applied, with the disease being more present mainly in pregnant women, with age being a key factor, in the age range between 20-24 and 30-34 years. The prevalence of the disease was shown to be 8.63% among the aforementioned age range, that is, for every 1,000 pregnant women, 9 women suffer from obstetric antiphospholipid syndrome or a related disease. Conclusions: obstetric antiphospholipid syndrome affects women of childbearing age and is the main cause of recurrent abortions, most of which occur after ten weeks. The high risk record of preterm birth is related to this obstetric antiphospholipid syndrome.
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References
2. Pérez M, Jiménez L, Mérida F. Impacto social del síndrome antifosfolípido: su incidencia en la calidad de vida de los pacientes. EDUMECENTRO [Internet] 2022 [citado 5 Oct 2023]; 14:[aproximadamente 12 p.]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S2077-28742022000100098
3. Bustillos A. Síndrome Antifosfolipídico Obstétrico: revisión bibliográfica del manejo en cuanto a diagnóstico y tratamiento. Ecuador: Universidad central del Ecuador, Facultad de Ciencias Químicas Bioquímica Clínica; 2020. Disponible en: http://www.dspace.uce.edu.ec/bitstream/25 000/23330/1/T-UCE-0008-CQU-310.pdf
4. Bencardino CM. Estadística básica aplicada. 5 ed. Bogotá: EcoeEdiciones; 2019.
5. Chérrez Y, Arévalo J. Misoprostol Vs Legrado Uterino Instrumental en el tratamiento del aborto incompleto. Hospital Carlos Andrade Marín. Quito, 2020-2021. [Tesis de grado]. Ecuador: Universidad Nacional de Chimborazo, Facultad de Ciencias de la Salud; 2021.
6. Paredes Izurieta MC. Análisis de factores de riesgo de preeclampsia en mujeres atendidas en el Hospital San Vicente de Paúl en el año 2020 [Tesis]. Ecuador: PUCESE; 2022 [citado 5 Oct 2023]. Disponible en: https://repositorio.pucese.edu.ec/handle/123456789/3133
7. Puig K. Perspectivas de cuidados de enfermería en el embarazo de alto riesgo [Tesis]. Ecuador: Universidad Estatal de Milagro; 2021
8. Knight Jason S. Síndrome antifosfolípido: avances en diagnóstico, patogénesis y manejo (D. Ware & T. Ortel, Eds.); 2023. DOI: http://dx.doi.org/10.1136/%20bmj%C3%BF2021%C3%BF069717
9. Castro Gutiérrez A, Young K, Bermas BL. Embarazo y manejo en mujeres con artritis reumatoide, lupus sistémico Eritematoso y Síndrome Antifosfolípido Obstétrico. Rheum Dis Clin North Am [Internet] 2022 May [citado 27 Sep 2023]; 48(2):523-535. DOI: https://doi.org/10.1016/j.rdc.2022.02.009
10. Meroni P, Borgh MO, Chighizola C, Beatrice C. (Eds.). Síndrome antifosfolípido obstétrico y vascular: ¿mismos anticuerpos pero enfermedades diferentes? Macmillan; 2018. DOI: https://doi.org/10.1055/s%C2%AD0037%C2%AD1603936
11. Acuña-Valerio J, Peña-Duque MA, Contreras-Villaseñor Á. Trombosis primaria de la descendente anterior en un paciente con síndrome de anticuerpos antifosfolípidos. Gaceta de Méx. 2017; 153(4).
